Synthesis of heterodimer radionuclide nanoparticles for magnetic resonance and single-photon emission computed tomography dual-modality imaging.
نویسندگان
چکیده
We report a facile synthesis of bifunctional Fe3O4-Ag(125)I heterodimers for use as dual-modality imaging agents in magnetic resonance (MR) and single-photon emission computed tomography (SPECT). We introduced (125)I, which is a clinically used radioisotope, as a SPECT reporter, into Fe3O4-Ag heterodimer nanoparticles to provide a new type of bifunctional contrast agent for MRI and SPECT imaging.
منابع مشابه
Brain Single Photon Emission Computed Tomography Scan (SPECT) and Functional MRI in Systemic Lupus Erythematosus Patients with Cognitive Dysfunction: A Systematic Review
Objective(s): Systemic lupus erythematosus (SLE) is an autoimmune disease with a wide range of clinical manifestations. Cognitive dysfunction is one of the manifestations that could present prior to the emergence of any other neuropsychiatric involvements in SLE. Cognitive dysfunction is a subtle condition occurring with ahigh frequency. However, there is no data on the correlation of cognitive...
متن کاملUtilization of an optimum low-pass filter during filtered back-projection in the reconstruction of single photon emission computed tomography images of small structures
Introduction:Low-pass filters eliminate noise, and accordingly improve the quality of filtered back-projection (FBP) in the reconstruction of single photon emission computed tomography (SPECT) images. This study aimed at selection of an optimum low-pass filter for FBP reconstruction of SPECT images of small structures. Material and Methods:Sp...
متن کاملBimodal magnetic resonance imaging-computed tomography nanoprobes: A Review
Bimodal imaging combines two imaging modalities in order to benefit from their advantages and compensate the limitations of each modality. This technique could accurately detect diseases for diagnostic purposes. Nanoparticles simultaneously offer diagnostic data via various imaging modalities owing to their unique properties. Moreover, bimodal nanoprobes could be incorporated into theranostic s...
متن کاملRadiolabeled Nanoparticles for Molecular Imaging
Molecular imaging (MI) comprises non-invasive monitoring of functional and spatiotemporal processes at molecular and cellular levels in humans and other living systems. In contrast to conventional diagnostic imaging, MI seeks to probe the molecular abnormalities that are the basis of disease rather than capture the images of the end effects of the molecular alterations. Imaging techniques such ...
متن کاملTargeted Magnetic Nanotheranostics of Cancer.
Current advances in targeted magnetic nanotheranostics are summarized in this review. Unique structural, optical, electronic and thermal properties of magnetic materials in nanometer scale are attractive in the field of biomedicine. Magnetic nanoparticles functionalized with therapeutic molecules, ligands for targeted delivery, fluorescent and other chemical agents can be used for cancer diagno...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Nanoscale
دوره 7 8 شماره
صفحات -
تاریخ انتشار 2015